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Patents

Patents.

11

Detappe A. Process for conjugation-ratio-controlled release of conjugated proteins from hydrogel matrices, EP26300216.4, 2026 – patent licensed

10

Charbonnière L, Tsvetkov P, Detappe A, Zhu C, Mishra P, Selvaratnam A, Banerjee M, Ralahy B. Elesclomol derivatives and use thereof. EP26300125.7, 2026

9

Detappe A, Tillement O, David L, Tillement A, Belarouci E, Lux F, Grange C, Jacquot G. Pharmaceutical formulation comprising a protein and functionalized chitosan for subcutaneous administration. WO2026/008804, 2026 – Patent licensed

8

Detappe A, Ghosh S, Draussin J, Lopez Navarro P. Complexe peptidique radiosensibilisant. FR2042983, 2025

7

Detappe A, Grange C. Process for long-term storage of proteins. EP25306906, 2025

6

Tillement A, Tillement T, Tillement O, Lux F, David L, Duroux C, Rossetti F, Decker Y, Fassbender K, Labrune E, Salle B, Deutsch E, Morel D, Cassagnau P, Gillet P, Vourc’h M, Chevalier P, Pivot X, Detappe A. Procédé de diagnostic, pronostic et/ou de suivi thérapeutique de maladies impactant le profil minéral d’au moins un fluide biologique, ainsi qu’un dispositif, un système et un logiciel utiles pour sa mise en œuvre. FR2402722, 2024

5

Detappe A, Pivot X, Coliat P, Tillement O, Lux F, David L, Grea T. Pharmaceutical formulation for subcutaneous administration of proteins. WO2023/148351 A1, 2023 – patent licensed

4

Johnson JA, Nguyen HVTN, Jiang Y, Detappe A, Agius M, Ghobrial IM. Proteolysis targeting chimeric molecules (PROTACS) with functional handles and uses thereof. US 2021/0220391, 2021

3

Johnson JA, Nguyen HVTN, Jiang Y, Detappe A, Agius M, Ghobrial IM. Boronic ester prodrugs and uses thereof. US 2020/0369685A1, 2020 – patent licensed

2

Detappe A, Ghobrial IM, Reidy M, Ghoroghchian PP. B-cell Maturation Antigen (BCMA)-directed nanoparticles. WO2018/231949 A1, 2018 – patent licensed

1

Berbeco RI, Detappe A, Thomas E, Le Duc G, Lux F, Tillement O. Bismuth-gadolinium nanoparticles for MRI-guided radiation therapy. WO2018107057A1, 2018