PUBLICATIONS - 2024
56. REINFORCED POLYMER-NANOPARTICLE HYDROGELS FOR SUBCUTANEOUS AND SUSTAINED DELIVERY OF TRASTUZUMAB
Bovone G , Bernhard S, Jacquot J, Mittelheisser V, Mirjolet C, Guzzi E , Paganella LG, Liebi L, Lefebvre O, Goetz J, Charbonnière LJ, Harlepp S, Pivot X, Tibbitt MW*, Detappe A*. BioRxiv 2024
Jacquot G, Lopez Navarro P, Grange C, Boudali L, Harlepp S, Pivot X, Detappe A. Adv Mater 2024
Vaur V, Koutsopetras I, Erb S, Jackowska B, Benazza R, Cahuzac H, Detappe A, Hernandez-Alba O, Cianférani S, Scott CJ, Chaubet G.Chemical Production of Cytotoxic Bispecific Antibodies Using the Ugi Multicomponent Reaction. Vaur V, Koutsopetras I, Erb S, Jackowska B, Benazza R, Cahuzac H, Detappe A, Hernandez-Alba O, Cianférani S, Scott CJ, Chaubet G. Chembiochem 2024
Mathieu C†, Ghosh S†, Draussin J, Gasser A, Jacquot G, Banerjee M, Gupta T, Schmutz M, Mirjolet C, Tillement O, Lux F, Klymchenko A, Donzeau M, Pivot X, Harlepp S, Detappe A*. Adv Healthc Mater 2024
PUBLICATIONS - 2023
Koutsopetras I, Vaur V, Benazza R, Diemer H, Sornay C, Ersoy Y, Rochet L, Longo C, Hernandez-Alba O, Erb S, Detappe A, Skerra A, Wagner A, Cianferani S, Chaubet G*. Chem. Eur. J. 2023
Gréa T, Jacquot G, Durand A, Mathieu C, Gasser A, Zhu C, Banerjee M, Hucteau E, Mallard J, Popescu BV, Thomas E, Kryza D, Sidi-Boumedine J, Ferrauto G, Gianolio E, Fleith G, Combet J, Brun S, Erb S, Cianferani S, Charbonnière LJ, Fellmann L, Mirjolet C, David L, Tillement O, Lux F, Harlepp S, Pivot X, Detappe A*. Adv Mater 2023
Coliat P, Erb S, Diemer H, Karouby D, Banerjee M, Zhu C, Demarchi M, Cianferani S, Detappe A, Pivot X*, Sci. Rep. 2023
Cui G, Botuyan MV, Drane P, Hu Q, Bragantini B, Thompson JR, Schuller DJ, Detappe A, Perfetti MT, James LI, Frye SV, Chowdhury D*, Mer G*. Nat Commun 2023
Carmès L†, Banerjee M†, Coliat P, Harlepp S, Pivot X, Tillement O, Lux F, Detappe A*. Adv Therapeutics 2023
Detappe A†, Nguyen HVTN†, Jiang Y, Agius MP, Wang W, Mathieu C, Su NK, Kristufek SL, Lundberg DJ, Bhagchandani S, Ghobrial IM*, Ghoroghchian PP*, Johnson JA*. Nat Nanotech 2023
- Nature Nanotechnology News&Views: https://www.nature.com/articles/s41565-022-01265-3
- MIT News: https://news.mit.edu/2023/targeting-cancer-multidrug-nanoparticle-0126
- Science China Materials: https://link.springer.com/article/10.1007/s40843-023-2482-8
46. CLINICALLY TRANSATABLE TRANSCROCETIN DELIVERY PLATFORM FOR CORRECTION OF TUMOR HYPOXIA AND ENHANCEMENT OF RADIATION THERAPY EFFECTS
Diringer MC, Coliat P, Mathieu C, Laurent N, Mura C, Banerjee M, Zhu C, Grabowska A, Ritchie A, Clarke P, Bernard A, Vit C, Burckel H, Noel G, Harvey P, Pivot X, Detappe A*. Small 2023
PUBLICATIONS - 2022
45. A COMBINATION OF NATIVE LC-MS APPROACHES FOR THE COMPREHENSIVE CHARACTERIZATION OF THE ANTIBODY-DRUG CONJUGATE TRASTUZUMAB-DERUXTECAN
Desligniere E, Diemer H, Erb S, Coliat P, Pivot X, Detappe A, Hernandez-Alba O, Cianferani S*. Front Biosci 2022.
44. LEAF- 4L6715 ENHANCES OXYGENATION IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) DUE TO SEVERE COVID-19: FINAL RESULTS OF A PHASE I/II CLINICAL TRIAL
Mertes PM, Delabranche X, Coliat P, Roche A, Collange O, Voegelin M, Bernard A, Dhindsa N, Xu ZH, Geng B, Niyikiza C, Moyo V, Bourban C, Villa P, Detappe A*, Pivot X*. MedRxiv 2022
Mittelheisser V, Coliat P, Moeglin E, Goepp L, Goetz JG, Charbonnière LJ, Pivot X, Detappe A*. Adv Mat. 2022
- CNRS press release: https://www.alsace.cnrs.fr/fr/cnrsinfo/cancer-et-chimiotherapie-ciblee-trois-questions-alexandre-detappe-et-vincent-mittelheisser
- University of Strasbourg press release: https://crbs.unistra.fr/actualites/actualite/mieux-cibler-tumeurs-cancereuses-nanoparticules-specifiques-encapsulant-anticorps-therapeutiques
PUBLICATIONS - 2021
Thomas E, Mathieu C, Moreno-Gaona P, Mittelheisser V, Lux F, Tillement O, Pivot X, Ghoroghchian PP, Detappe A*. Adv Healthc Mater. 2021
Demarchi M, Coliat P, Mclendon K, Hi JCS, Feyaerts P, Ang F, Jaison L, Deforce F, Derde MP, Kim MJ, Park LS, Detappe A, Pivot X*. Pharmacol Res Perspect. 2021
Mertes PM, Olivier Collange O, Coliat P, Banerjee M, Diringer MC, Roche A, Delabranche X, Chaban V, Voegelin M, Bernard A, Sartori V, Laurent N, Velten M, Dhindsa N, Defuria J, Kim G, Xu ZH, Theodorou M, Huang ZR, Khalifa K, Geng B, Niyikiza C, Moyo V, Gizzi P, Villa P, Detappe A*, Xavier Pivot X*. J Control Release 2021
Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, Busnelli I, Delalande F, Paul N, Halary S, Gros F, Fouillen L, Haeberle AM, Royer C, Spegelhalter C, André-Grégoire G, Mittelheisser V, Detappe A, Murphy K, Timpson P, Carapito R, Blot-Chabaud J, Gavard J, Carapito C, Vitale N, Lefebvre O, Goetz JG, Hyenne V. Elife 2021
PUBLICATIONS - 2020
Mittelheisser V, Banerjee M, Pivot X, Charbonnière L, Goetz J, Detappe A*. Adv Ther. 2020
Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S, Kelso S; MC3 Working Group; PCAWG novel somatic mutation calling methods working group, Saksena G, Ellrott K, Wendl MC, Wheeler DA, Getz G, Simpson JT, Gerstein MB, Ding L; PCAWG Consortium. Nat Commun 2020
Nguyen HVTN†, Detappe A†, Harvey P, Gallagher N, Mathieu C, Agius MP, Zavidij O, Wang W, Jiang J, Rajca A, Jasanoff A, Ghobrial IM, Ghoroghchian PP*, Johnson JAJ*. Polym Chem. 2020
Virani NA, Kelada OJ, Kunjachan S, Detappe A, Kwon J, Hayashi J, Vasquez-Pagan A, Biancur DE, Ireland T, Kumar R, Sridhar S, Makrigiorgos GM, Berbeco RI*. Plos One. 2020
Detappe A*, Mathieu C, Jin C, Agius MP, Diringer MC, Tran VL, Pivot X, Lux F, Tillement O, Kufe D*, Ghoroghchian PP*. Int J Radiat Oncol Biol Phys. 2020
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Nature. 2020
PUBLICATIONS - 2019
Detappe A, Reidy M, Yu Y, Mathieu C, Nguyen HV, Coroller TP, Lam F, Jarolim P, Harvey P, Protti A, Nguyen QD, Johnson JA, Cremillieux Y, Tillement O, Ghobrial IM*, Ghoroghchian PP*. Nanoscale. 2019
Patil R, Tan X, Bartosik P, Detappe A, Runnels JM, Ghobrial IM, Lin CP, Niedre M*, J Biomed Opt. 2019
Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M, Kory N, Tsherniak A, Santagata S, Whitesell L, Ghobrial IM, Markley JL, Lindquist S, Golub TR. Nat Chem Biol 2019
Kunjachan S, Kotb S, Pola R, Pechar M, Kumar R, Singh B, Gremse F, Taleeli R, Trichard F, Motto-Ros V, Sancey L, Detappe A, Yasmin-Karim S, Protti A, Shanmugam I, Ireland T, Etrych T, Sridhar S, Tillement O, Makrigiorgos M, Berbeco RI. Sci Rep. 2019
Lux F, Tran VL, Thomas E, Dufort S, Rossetti F, Martini M, Truillet C, Doussineau T, Bort G, Denat F, Boschetti F, Angelovski G, Detappe A, Crémillieux Y, Mignet N, Doan BT, Larrat B, Meriaux S, Barbier E, Roux S, Fries P, Müller A, Abadjian MC, Anderson C, Canet-Soulas E, Bouziotis P, Barberi-Heyob M, Frochot C, Verry C, Balosso J, Evans M, Sidi-Boumedine J, Janier M, Butterworth K, McMahon S, Prise K, Aloy MT, Ardail D, Rodriguez-Lafrasse C, Porcel E, Lacombe S, Berbeco R, Allouch A, Perfettini JL, Chargari C, Deutsch E, Le Duc G, Tillement O. Br J Radiol. 2019
PUBLICATIONS - 2018
He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, De S, Konstantinopoulos PA, Masson JY, Chowdhury D. Nature. 2018
Nguyen HV*, Detappe A*, Gallagher NM, Zhang H, Harvey P, Yan C, Mathieu C, Golder MR, Jiang Y, Ottaviani MF, Jasanoff A, Rajca A, Ghobrial I, Ghoroghchian PP, Johnson JA. ACS Nano. 2018. *equal contribution
Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G. Nat Struct Mol Biol. 2018
Detappe A, Bustoros M, Mouhieddine TH, Ghoroghchian PP. Trends Mol Med. 2018
Kurdi AT, Glavey SV, Bezman NA, Jhatakia A, Guerriero JL, Manier S, Moschetta M, Mishima Y, Roccaro A, Detappe A, Liu CJ, Sacco A, Huynh D, Tai YT, Robbins MD, Azzi J, Ghobrial IM. Mol Cancer Ther. 2018
Meghani K, Fuchs W, Detappe A, Drané P, Gogola E, Rottenberg S, Jonkers J, Matulonis U, Swisher EM, Konstantinopoulos PA, Chowdhury D. Cell Rep. 2018
21. DIFFERENCES IN NANOPARTICLE UPTAKE IN TRANSPLANTED AND AUTOCHTHONOUS MODELS OF PANCREATIC CANCER
Tao Z, Muzumdar MD, Detappe A, Huang X, Xu ES, Yu Y, Mouhieddine TH, Song H, Jacks T, Ghoroghchian PP. Nano Lett. 2018
Ghobrial IM, Detappe A, Anderson KC, Steensma DP. Nat Rev Clin Oncol. 2018
PUBLICATIONS - 2017
Qi R, Wang Y, Bruno PM, Xiao H, Yu Y, Li T, Lauffer S, Wei W, Chen Q, Kang X, Song H, Yang X, Huang X, Detappe A, Matulonis U, Pepin D, Hemann MT, Birrer MJ, Ghoroghchian PP. Nat Commun. 2017
Hofmann CL, O'Sullivan MC, Detappe A, Yu Y, Yang X, Qi W, Landon CD, Therien MJ, Dewhirst MW, Ghoroghchian PP, Palmer GM. Nanoscale. 2017
Bustoros M, Mouhieddine TH, Detappe A, Ghobrial IM. Am Soc Clin Oncol Educ Book. 2017
Mishima Y, Paiva B, Shi J, Park J, Manier S, Takagi S, Massoud M, Perilla-Glen A, Aljawai Y, Huynh D, Roccaro AM, Sacco A, Capelletti M, Detappe A, Alignani D, Anderson KC, Munshi NC, Prosper F, Lohr JG, Ha G, Freeman SS, Van Allen EM, Adalsteinsson VA, Michor F, San Miguel JF, Ghobrial IM. Cell Rep. 2017
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D. Nature. 2017
Detappe A, Thomas E, Tibbitt MW, Kunjachan S, Zavidij O, Parnandi N, Reznichenko E, Lux F, Tillement O, Berbeco R. Nano Lett. 2017
PUBLICATIONS - 2016
Detappe A, Kunjachan S, Drané P, Kotb S, Myronakis M, Biancur DE, Ireland T, Wagar M, Lux F, Tillement O, Berbeco R. Sci Rep. 2016
Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R. J Control Release. 2016
Appelboom G, Detappe A, LoPresti M, Kunjachan S, Mitrasinovic S, Goldman S, Chang SD, Tillement O. Neuro Oncol. 2016
Detappe A, Lux F, Tillement O. Nanomedicine (Lond). 2016
Kotb S, Detappe A, Lux F, Appaix F, Barbier EL, Tran VL, Plissonneau M, Gehan H, Lefranc F, Rodriguez-Lafrasse C, Verry C, Berbeco R, Tillement O, Sancey L. Theranostics. 2016
Mitrasinovic S, Appelboom G, Detappe A, Sander Connolly E Jr. J Clin Neurosci. 2016
Berbeco RI, Detappe A, Tsiamas P, Parsons D, Yewondwossen M, Robar J. Med Phys. 2016
PUBLICATIONS PRIOR 2016
Kunjachan S, Detappe A, Kumar R, Ireland T, Cameron L, Biancur DE, Motto-Ros V, Sancey L, Sridhar S, Makrigiorgos GM, Berbeco RI. Nano Lett. 2015
Detappe A, Kunjachan S, Rottmann J, Robar J, Tsiamas P, Korideck H, Tillement O, Berbeco R. Cancer Nanotechnol. 2015
Lux F, Detappe A, Dufort S, Sancey L, Louis C, Carme S, Tillement O. Cancer Radiother. 2015
Altundal Y, Cifter G, Detappe A, Sajo E, Tsiamas P, Zygmanski P, Berbeco R, Cormack RA, Makrigiorgos M, Ngwa W. Phys Med. 2015
Sancey L, Lux F, Kotb S, Roux S, Dufort S, Bianchi A, Crémillieux Y, Fries P, Coll JL, Rodriguez-Lafrasse C, Janier M, Dutreix M, Barberi-Heyob M, Boschetti F, Denat F, Louis C, Porcel E, Lacombe S, Le Duc G, Deutsch E, Perfettini JL, Detappe A, Verry C, Berbeco R, Butterworth KT, McMahon SJ, Prise KM, Perriat P, Tillement O. Br J Radiol. 2014
Detappe A, Tsiamas P, Ngwa W, Zygmanski P, Makrigiorgos M, Berbeco R. Med Phys. 2013